Are You an Active Substance User? 
No Judgments Here…Just Help

Questions? Get in touch:
Anabelle Soto
(212) 645-0875 x125

In 2016, the Lower East Side Harm Reduction Center joined the Alliance. Born in the midst of the AIDS crisis, the Lower East Side Harm Reduction Center is a culturally diverse, community based, non-profit organization. Its mission: reduce the spread of HIV/AIDS, HCV and other drug-related harm among injection drug users. Its professionals and volunteers deliver substance use-management services with anonymity and compassion, while also training others in the practice compassionate intervention.

Visitors to Alliance LES Harm Reduction Center can:

  • Exchange syringes in complete anonymity

  • Get sterile injecting equipment and safer sex supplies

  • Receive Narcan/Naloxone overdose prevention meds and learn essential practices and procedures.

  • Be tested for HIV or hepatitis C (Rapid testing)

  • Get medical and mental health care, counseling, and referrals

  • Sign up for case management

For Overdose Prevention Training, contact:
Reilly Glasgow
(212) 645-0875 x146

To become a volunteer, contact:
Melissa Sandel
(212) 645-0875 x103

We Train Peers to Reach Out

Since 1995, the Positive Action Peer Education Program (PAPEP) has trained more than 200 recovering addicts for employment or volunteer work as peer counselors.

The mission: Reach out to the Lower East Side community by providing education in the prevention and treatment of HIV and hepatitis. As part of this training, program participants learn the principles of harm reduction, including how to conduct community outreach and organizing efforts.

Many PAPEP graduates are now employed full time in various social service organizations; others are now Alliance LES Harm Reduction Center community outreach volunteers.


Visit our drop-in center at:
25 Allen Street
New York, NY 10002

Or call us at 212-645-0875, x100


Syringe Exchange
Monday - Friday: 10am - 8pm
Saturday: 10am - 5pm

Counseling Services
Monday- Friday: 9am - 5pm

Monday-Friday: 10am - 3 pm
(Or call 212-645-0875, x100 for an appointment)

Getting Here:

  • F Train to East Broadway

  • B or D Train to Grand Street

  • M15 Bus to Hester & Allen Street

Drop-In Center
Monday: 9am-7:30pm
Tuesday: CLOSED
Wednesday-Friday: 9am-7:30pm
Saturday: 2pm-4:30pm

Get Tested.

Testing is the #1 tool against HIV and
hepatitis C.

Make a Donation.

Support the next great transformation
at the Alliance.